I don't think the genders are different, but we get treated differently. It can be very helpful to learn how the "other side" sees things.
I have a good friend of mine who is extremely, completely male, in his interests, dress, the state of his room, everything. He's also gay. That makes sense to me. Femininity to him is a cipher, it's incomprehensible. Why would he want to spend time with any women?