I've been on wellbutrin for about 6 months, and for me, it's working wonders. I've had to stop taking it at nighttime (read as after 7 pm) as it keeps me so level I don't sleep.
In researching my family history, severe depression keeps rearing its ugly head. So it comes as no surprise (now) that I inherited this problem along with a few others.
I've found counseling is needed, and right now, my psychiatrist is doing a great job in helping me with dealing with the bumps.
I find that everyone responses differently to medication, so the best bet is to talk to a psychiatrist and put together a plan of action. It took me 3 tries to find the right medication to keep me level.
For a lot of the anti-depressants to work, you have to maintain dosage about 1-2 weeks. However, if you "zombie" out, a dosage reduction or medication change is needed. The idea is that they reduce the depression level and leave you able to function (almost) normally.
Just some of my thoughts.....