I'd say 99% of my friends are guys, and two of which are my best friends and I have very close relationships with. I have one best friend who is a female and a few female aquaitences but that's it. I definetly have more guy friends. I've never thought of my guy friends in any other way but friends and I'm pretty sure we are all on the same level. I find it easier for me to get along with males easier then females. I love my my male friends minds, it amazes me because you look at everything in a different way then you would if they were your significant other. It is definetly POSSIBLE, speaking from experience. As far as it being a problem in a relationship with say my boyfriend I'm just upfront and honest from the start, i'll let my boyfriend know "hey look, so and so is my best friend and it's as far as it goes and that my relationship w/the friend is not going to change." if he has a problem with that, then that is a problem to me. I've never had any problems because I was upfront about it, and my boyfriends have met my male friends. As a matter of fact my current bf is friends w/all my guy friends as well so it works out pretty good. This is just my OP of course.