Vitamins : Part 4

How and When To Be Your Own Doctor
by Dr. Isabelle A. Mose, Steve Solomon

(Page 10 of 14)

Because deterioration starts out so slowly, people usually do not begin to notice there has been any decline until they reach their late 30s. A few fortunate ones don't notice it until their 40s. A few (usually) dishonest ones claim no losses into their 50s but they are almost inevitably lying, either to you or to themselves, or both. Though it might be wisest to begin combating the aging process at age 19, practically speaking, no one is going to start spending substantial money on food supplements until they actually notice significant lost function. For non-athletes this point usually comes when function has dropped to about 90 percent of what it was in our youth. If they're lucky what people usually notice with the beginnings of middle age is an increasing inability for their bodies to tolerate insults such as a night on the town or a big meal. Or they may begin to get colds that just won't seem to go away. Or they may begin coming home after work so tired that they can hardly stay awake and begin falling asleep in their Lazy Boy recliner in front of the TV even before prime time. If they're not so lucky they'll begin suffering the initial twinges of a non-life-threatening chronic condition like arthritis.

The thinnest line demonstrates the worst possible life from a purely physical point of view, where a person started out life with significantly lowered function, lost quite a bit more and then hung on to life for many years without the mercy of death.

If one can postpone the deterioration of aging, they extend and hopefully square the curve (retard loss of function until later and then have the loss occur more rapidly). Someone whose lifetime function resembled a 'square curve'(the thickest, topmost line) would experience little or no deterioration until the very end and then would lose function precipitously. At this point we do not know how to eliminate the deterioration but we do know how to slow it down, living longer and feeling better, at least to a point close to the very end.

Vitamin supplements can actually slow or even to a degree, reverse, the aging process. However, to accomplish that task, they have to be taken in amounts far greater than so-called minimum daily requirements, using vitamins as though they were drugs, a therapeutic approach to changing body chemistry profiles and making them resemble a younger body. For example, research gerontologists like Walford reason that if pantothenic acid (vitamin B 5, in fairly substantial (but quite safe) doses can extend the life and improve the function of old rats, there is every indication that it will do a similar job on humans. Medical researchers and research gerontologists have noticed that many other vitamin and vitamin-like substances have similar effects on laboratory animals.

Some will object that what helps rats and mice is in no way proven to cause the same result on humans. I agree. Proven with full scientific rigor, no. In fact, at present, the contention is unprovable. Demonstrable as having a high likelihood's of being so, yes! So likely so as to be almost incontrovertible, yes! But provable to the most open-minded, scientific sort - probably not for a long time. However, the Life Extension Foundation is working hard to find some quantifiable method of gauging the aging process in humans without waiting for the inarguable indicator, death. Once this is accomplished and solidly recognized, probably no rational person will be able to doubt that human life span can be increased.

Experiments work far better with short-lived laboratory animals for another reason; we can not control the food and supplement intakes of humans as we can with caged mice. In fact, there are special types of laboratory mice that have been bred to have uniformly short life spans, especially to accelerate this kind of research. With mice we can state accurately that compared to a control group, feeding such and such a dose of such and such a supplement extended the life-span or functional performance by such and such a percent.

A lot of these very same medical gerontologists nourish their own bodies as thoroughly as the laboratory animals they are studying, taking broad mixes of food supplements at doses proportional to those that extend the life spans of their research animals. This approach to using supplementation is at the other end of the scale compared to using supplements to prevent gross deficiencies. In the life extension approach, vitamins and vitamin-like substances are used as a therapy against the aging process itself.

Will it work? Well, some of these human guinea pigs have been on heavy vitamin supplementation for over thirty years (as of 1995) and none seem to be suffering any damage. Will they live longer? It is impossible to say with full scientific rigor? To know if life extension works, we would have to first determine 'live longer than what?' After all, we don't know how long any person might have lived without life extending vitamin supplements. Though it can't be 'proven,' it makes perfect sense to me to spend far less money on an intensive life extension vitamin program than I would certainly lose as a result of age-related sickness.

Besides, I've already observed from personal use and from results in my clinical practice that life extension vitamin programs do work. Whether I and my clients will ultimately live longer or not, the people who I have put on these programs, including myself and my husband, usually report that for several years after starting they find themselves feeling progressively younger, gradually returning to an overall state of greater well-being they knew five or ten or fifteen years ago. They have more energy, feel clearer mentally, have fewer unwanted somatic symptoms.

Sometimes the improvements seem rather miraculous. After a few months on the program one ninety year old man, an independent-minded Oregonian farmer, reported that he began awakening with an erection every morning; unfortunately, his 89 year old cranky and somewhat estranged wife, who would not take vitamins, did not appreciate this youthfulness. A few months later (he had a small farm) he planted a holly orchard. Most of you won't appreciate what this means without a bit of explanation, but in Oregon, holly is grown as a high-priced and highly profitable ornamental for the clusters of leaves and berries. But a slow-growing holly orchard takes 25 years to began making a profit!