Hepatitis A : Frequently Asked Questions

by CDC

What is hepatitis A?

Hepatitis A is a liver disease caused by hepatitis A virus.

How is hepatitis A virus transmitted?

Hepatitis A virus is spread from person to person by putting something in the mouth that has been contaminated with the stool of a person with hepatitis A. This type of transmission is called "fecal-oral." For this reason, the virus is more easily spread in areas where there are poor sanitary conditions or where good personal hygiene is not observed.

Most infections result from contact with a household member or sex partner who has hepatitis A. Casual contact, as in the usual office, factory, or school setting, does not spread the virus.

What are the signs and symptoms of hepatitis A?

Persons with hepatitis A virus infection may not have any signs or symptoms of the disease. Older persons are more likely to have symptoms than children. If symptoms are present, they usually occur abruptly and may include fever, tiredness, loss of appetite, nausea, abdominal discomfort, dark urine, and jaundice (yellowing of the skin and eyes). Symptoms usually last less than 2 months; a few persons are ill for as long as 6 months. The average incubation period for hepatitis A is 28 days (range: 15-50 days).

If you've had hepatitis A in the past, can you get it again?

No. Once you recover from hepatitis A you develop antibodies that provide life-long protection from future infections. After recovering from hepatitis A, you will never get it again and you cannot transmit the virus to others.

How do you know if you have hepatitis A?

A blood test (IgM anti-HAV) is needed to diagnose hepatitis A. Talk to your doctor or someone from your local health department if you suspect that you have been exposed to hepatitis A or any type of viral hepatitis.

How can you prevent hepatitis A?

Always wash your hands after using the bathroom, changing a diaper, or before preparing or eating food.

Two products are used to prevent hepatitis A virus infection: immune globulin and hepatitis A vaccine.

1. Immune globulin is a preparation of antibodies that can be given before exposure for short-term protection against hepatitis A and for persons who have already been exposed to hepatitis A virus. Immune globulin must be given within 2 weeks after exposure to hepatitis A virus for maximum protection.

2. Hepatitis A vaccine has been licensed in the United States for use in persons 12 months of age and older. The vaccine is recommended (before exposure to hepatitis A virus) for persons who are more likely to get hepatitis A virus infection or are more likely to get seriously ill if they do get hepatitis A. The vaccines currently licensed in the United States are HAVRIX® (manufactured by GlaxoSmithKline) and VAQTA® (manufactured by Merck & Co., Inc).

How do you kill hepatitis A virus (HAV)?

HAV can live outside the body for months, depending on the environmental conditions. HAV is killed by heating to 185 degrees F. (85 degrees C.) for one minute. However, HAV can still be spread from cooked food if it gets contaminated after cooking. Adequate chlorination of water, as recommended in the US, kills HAV that may get into the water supply.

Can I donate blood if I have had any type of viral hepatitis?

If you had any type of viral hepatitis since aged 11 years, you are not eligible to donate blood. In addition, if you ever tested positive for hepatitis B or hepatitis C, at any age, you are not eligible to donate, even if you were never sick or jaundiced from the infection.

Top of page Can I get viral hepatitis from an animal?

No. Hepatitis viruses are not zoonotic meaning that they cannot be transmitted between, or be shared by, animals and humans. No natural animal or insect hosts or vectors are known to exist. While humans are the only natural hosts, some non-human primates can be experimentally infected for research purposes.

Hepatitis A Vaccine and Immune Globulin

Can a patient receive the first dose of hepatitis A vaccine from one manufacturer and the second (last) dose from another manufacturer?

Yes. Although studies have not been done to look at this issue, there is no reason to believe that this would be a problem.

About the Author

www.cdc.gov
The Centers for Disease Control and Prevention (CDC) is one of the 13 major operating components of the Department of Health and Human Services (HHS), which is the principal agency in the United States government for protecting the health and safety of all Americans and for providing essential human services, especially for those people who are least able to help themselves.